HLA B*5701
HLA-B57:01 (HLA B*5701, HLA-B*57:01) is a human leukocyte antigen allele associated with hypersensitivity reactions to the antiretroviral drug abacavir, used in HIV treatment. Screening for the presence of HLA-B57:01 prior to therapy initiation is critical to prevent severe, potentially life-threatening immune responses in susceptible individuals.
HLA-B57:01 PCR kits based on real-time PCR technology provide a sensitive and specific method for detecting the HLA-B57:01 allele in human genomic DNA. These molecular testing tools deliver accurate and reproducible results in routine and specialized laboratory workflows used in genetic testing laboratories. Available in research use only (RUO) format, this PCR assay supports a wide range of applications including pharmacogenetic screening from clinical samples, personalized HIV treatment planning, and HLA typing.