Leucosis / BCR-ABL

The BCR-ABL fusion gene is a hallmark of chronic myeloid leukemia (CML) and is also found in some cases of acute lymphoblastic leukemia (ALL). This genetic abnormality results from a translocation between chromosomes 9 and 22, forming the Philadelphia chromosome. Precise and sensitive detection of BCR-ABL is essential for diagnosis, treatment monitoring, and minimal residual disease (MRD) assessment.
BCR-ABL PCR kits based on real-time PCR technology provide a highly specific and sensitive method for detecting and quantifying bcr-abl сDNA of the bcr-abl chimeric gene area in human samples. These molecular diagnostics tools deliver accurate and reproducible results in routine and specialized laboratory workflows. Available in CE IVD-marked format for diagnostic use and research use only (RUO) version, these PCR assays allows the detection of CML (chronic myelogenous leukemia) associated with M-bcr-abl chromosomal rearrangement and support a wide range of applications including leukemia diagnostics from clinical samples, therapy response monitoring, and long-term disease tracking.