Ecoli Dx Products Drug resistance Genetic markers of antibiotic resistance

Genetic markers of antibiotic resistance

Detection of genetic markers linked to antibiotic resistance is critical for guiding effective antimicrobial therapy and combating multidrug-resistant (MDR) infections. These markers include genes encoding enzymes and proteins that confer resistance to a broad spectrum of antibiotics. Key targets include:
KPC and OXA-48 carbapenemases, responsible for resistance to last-resort β-lactam antibiotics.
Metallo-β-lactamases (MBL) such as NDM, VIM, and IMP, which hydrolyze carbapenems and other β-lactams.
MCR-1, a plasmid-mediated colistin resistance gene.
Vancomycin-resistant Enterococci (VRE) markers such as vanA and vanB.
Real-time PCR kits enable rapid, sensitive, and specific detection of these genetic markers from clinical specimens in routine and specialized laboratory workflows. Available in CE IVD-marked and research use only (RUO) formats, these PCR assays support antimicrobial stewardship programs, infection control, and epidemiological surveillance by providing timely resistance gene identification from clinical samples.

Brands
Certification
Availability
Format
Catalogue number
ES4302A
Product name
eSens MDR KPC/OXA QL PCR kit
IFU
Availability
More Info
▼
Detection
Real-Time PCR
Format
Reagents in stock tubes
Reactions
110
Certification
CE marked as legacy IVD
Fluorescent channels
Green FAM/SYBR Green I Yellow HEX/JOE/VIC Orange ROX
Detail
qualitative

Specifics

  • Brand: eSens
  • Certification: CE marked as legacy IVD
  • Detection: Real-Time PCR
  • Fluorescent channels: Green FAM/SYBR Green I, Yellow HEX/JOE/VIC, Orange ROX
  • Format: Reagents in stock tubes
  • Shelf life: 24
  • Detail: qualitative
  • Reactions: 110
  • Availability: on request

Assay targets:

  • acquired carbapenems genes from KPC and OXA-48-like (OXA-48- and OXA-162-type) types

Identical composition and protocol to (AmpliSens alternative):

  • R-C2(RG,CFX)-CE / AmpliSens® MDR KPC/OXA-48-FRT PCR kit

Documents to download:

Catalogue number
ES4301A
Product name
eSens MDR MBL QL PCR kit
IFU
Availability
More Info
▼
Detection
Real-Time PCR
Format
Reagents in stock tubes
Reactions
110
Certification
CE marked as legacy IVD
Fluorescent channels
Red Cy5 Green FAM/SYBR Green I Yellow HEX/JOE/VIC Orange ROX
Detail
qualitative

Specifics

  • Brand: eSens
  • Certification: CE marked as legacy IVD
  • Detection: Real-Time PCR
  • Fluorescent channels: Green FAM/SYBR Green I, Yellow HEX/JOE/VIC, Red Cy5, Orange ROX
  • Format: Reagents in stock tubes
  • Shelf life: 24
  • Detail: qualitative
  • Reactions: 110
  • Availability: available

Assay targets:

  • acquired carbapenems genes of metallo-β-lactamase class, types IMP, VIM, and NDM

Identical composition and protocol to (AmpliSens alternative):

  • R-C1(RG,CFX)-CE / AmpliSens® MDR MBL-FRT PCR kit

Documents to download:

Catalogue number
ES4304A
Product name
eSens MDR MCR-1 QL PCR kit
IFU
Availability
More Info
▼
Detection
Real-Time PCR
Format
Reagents in stock tubes
Reactions
110
Certification
CE marked as legacy IVD
Fluorescent channels
Green FAM/SYBR Green I Yellow HEX/JOE/VIC Orange ROX
Detail
qualitative, variant FRT-100 F

Specifics

  • Brand: eSens
  • Certification: CE marked as legacy IVD
  • Detection: Real-Time PCR
  • Fluorescent channels: Green FAM/SYBR Green I, Yellow HEX/JOE/VIC, Orange ROX
  • Format: Reagents in stock tubes
  • Shelf life: 24
  • Detail: qualitative, variant FRT-100 F
  • Reactions: 110
  • Availability: on request

Assay targets:

  • plasmid-encoded mcr-1 colistin resistance genes and marker genes of enterobacteria (Enterobacterales order) (16S rRNA genes)

Identical composition and protocol to (AmpliSens alternative):

  • HN-4171-1-CE / AmpliSens® MDR MCR-1-FRT PCR kit. variant FRT-100 F

Documents to download:

Catalogue number
ES4303A
Product name
eSens MDR VRE QL PCR kit
IFU
Availability
More Info
▼
Detection
Real-Time PCR
Format
Reagents in stock tubes
Reactions
110
Certification
CE marked as legacy IVD
Fluorescent channels
Red Cy5 Green FAM/SYBR Green I Yellow HEX/JOE/VIC Orange ROX
Detail
qualitative, variant FRT-100 F

Specifics

  • Brand: eSens
  • Certification: CE marked as legacy IVD
  • Detection: Real-Time PCR
  • Fluorescent channels: Green FAM/SYBR Green I, Yellow HEX/JOE/VIC, Red Cy5, Orange ROX
  • Format: Reagents in stock tubes
  • Shelf life: 24
  • Detail: qualitative, variant FRT-100 F
  • Reactions: 110
  • Availability: on request

Assay targets:

  • Enterococcus spp. and vanA and vanB gene

Identical composition and protocol to (AmpliSens alternative):

  • HN-3891-1-CE / AmpliSens® MDR VRE-FRT PCR kit. variant FRT-100 F

Documents to download:

Catalogue number
R-C2(RG,CFX)-CE
Product name
AmpliSens® MDR KPC/OXA-48-FRT PCR kit
IFU
Availability
More Info
▼
Detection
Real-Time PCR
Format
Reagents in stock tubes
Reactions
110
Certification
Research Use Only
Fluorescent channels
Green FAM/SYBR Green I Yellow HEX/JOE/VIC Orange ROX
Detail
qualitative

Specifics

  • Brand: AmpliSens
  • Certification: Research Use Only
  • Detection: Real-Time PCR
  • Fluorescent channels: Green FAM/SYBR Green I, Yellow HEX/JOE/VIC, Orange ROX
  • Format: Reagents in stock tubes
  • Shelf life: 9
  • Detail: qualitative
  • Reactions: 110
  • Availability: on request

Assay targets:

  • acquired carbapenems genes from KPC and OXA-48-like (OXA-48- and OXA-162-type) types

Identical composition and protocol to (eSens alternative):

  • ES4302A / eSens MDR KPC/OXA QL PCR kit

Documents to download:

  • Instructions For Use can be downloaded using the IFU icon above
  • Guidelines
Catalogue number
R-C1(RG,CFX)-CE
Product name
AmpliSens® MDR MBL-FRT PCR kit
IFU
Availability
More Info
▼
Detection
Real-Time PCR
Format
Reagents in stock tubes
Reactions
110
Certification
Research Use Only
Fluorescent channels
Red Cy5 Green FAM/SYBR Green I Yellow HEX/JOE/VIC Orange ROX
Detail
qualitative

Specifics

  • Brand: AmpliSens
  • Certification: Research Use Only
  • Detection: Real-Time PCR
  • Fluorescent channels: Green FAM/SYBR Green I, Yellow HEX/JOE/VIC, Red Cy5, Orange ROX
  • Format: Reagents in stock tubes
  • Shelf life: 9
  • Detail: qualitative
  • Reactions: 110
  • Availability: available

Assay targets:

  • acquired carbapenems genes of metallo-β-lactamase class, types IMP, VIM, and NDM

Identical composition and protocol to (eSens alternative):

  • ES4301A / eSens MDR MBL QL PCR kit

Documents to download:

  • Instructions For Use can be downloaded using the IFU icon above
  • Guidelines
Catalogue number
HN-4171-1-CE
Product name
AmpliSens® MDR MCR-1-FRT PCR kit
IFU
Availability
More Info
▼
Detection
Real-Time PCR
Format
Reagents in stock tubes
Reactions
110
Certification
Research Use Only
Fluorescent channels
Green FAM/SYBR Green I Yellow HEX/JOE/VIC Orange ROX
Detail
qualitative, variant FRT-100 F

Specifics

  • Brand: AmpliSens
  • Certification: Research Use Only
  • Detection: Real-Time PCR
  • Fluorescent channels: Green FAM/SYBR Green I, Yellow HEX/JOE/VIC, Orange ROX
  • Format: Reagents in stock tubes
  • Shelf life: 15
  • Detail: qualitative, variant FRT-100 F
  • Reactions: 110
  • Availability: on request

Assay targets:

  • plasmid-encoded mcr-1 colistin resistance genes and marker genes of enterobacteria (Enterobacterales order) (16S rRNA genes)

Identical composition and protocol to (eSens alternative):

  • ES4304A / eSens MDR MCR-1 QL PCR kit

Documents to download:

  • Instructions For Use can be downloaded using the IFU icon above
Catalogue number
HN-3891-1-CE
Product name
AmpliSens® MDR VRE-FRT PCR kit
IFU
Availability
More Info
▼
Detection
Real-Time PCR
Format
Reagents in stock tubes
Reactions
110
Certification
Research Use Only
Fluorescent channels
Red Cy5 Green FAM/SYBR Green I Yellow HEX/JOE/VIC Orange ROX
Detail
qualitative, variant FRT-100 F

Specifics

  • Brand: AmpliSens
  • Certification: Research Use Only
  • Detection: Real-Time PCR
  • Fluorescent channels: Green FAM/SYBR Green I, Yellow HEX/JOE/VIC, Red Cy5, Orange ROX
  • Format: Reagents in stock tubes
  • Shelf life: 15
  • Detail: qualitative, variant FRT-100 F
  • Reactions: 110
  • Availability: on request

Assay targets:

  • Enterococcus spp. and vanA and vanB gene

Identical composition and protocol to (eSens alternative):

  • ES4303A / eSens MDR VRE QL PCR kit

Documents to download:

  • Instructions For Use can be downloaded using the IFU icon above
Catalogue number
HN-4172-1-4-CE
Product name
AmpliSens® MDR MCR-1-FRT PCR kit
IFU
Availability
More Info
▼
Detection
Real-Time PCR
Format
Ready-to-use PCR tubes
Reactions
96
Certification
Research Use Only
Fluorescent channels
Green FAM/SYBR Green I Yellow HEX/JOE/VIC Orange ROX
Detail
qualitative, variant FRT-L

Specifics

  • Brand: AmpliSens
  • Certification: Research Use Only
  • Detection: Real-Time PCR
  • Fluorescent channels: Green FAM/SYBR Green I, Yellow HEX/JOE/VIC, Orange ROX
  • Format: Ready-to-use PCR tubes
  • Shelf life: 15
  • Detail: qualitative, variant FRT-L
  • Reactions: 96
  • Availability: on request

Assay targets:

  • plasmid-encoded mcr-1 colistin resistance genes
  • plasmid-encoded mcr-1 colistin resistance genes and marker genes of enterobacteria (Enterobacterales order) (16S rRNA genes)

Documents to download:

  • Instructions For Use can be downloaded using the IFU icon above
Catalogue number
HN-3892-1-4-CE
Product name
AmpliSens® MDR VRE-FRT PCR kit
IFU
Availability
More Info
▼
Detection
Real-Time PCR
Format
Ready-to-use PCR tubes
Reactions
96
Certification
Research Use Only
Fluorescent channels
Red Cy5 Green FAM/SYBR Green I Yellow HEX/JOE/VIC Orange ROX
Detail
qualitative, variant FRT-L

Specifics

  • Brand: AmpliSens
  • Certification: Research Use Only
  • Detection: Real-Time PCR
  • Fluorescent channels: Green FAM/SYBR Green I, Yellow HEX/JOE/VIC, Red Cy5, Orange ROX
  • Format: Ready-to-use PCR tubes
  • Shelf life: 15
  • Detail: qualitative, variant FRT-L
  • Reactions: 96
  • Availability: on request

Assay targets:

  • Enterococcus species and vanA and vanB gene (Vancomycin-Resistant Enterococcus - VRE)

Documents to download:

  • Instructions For Use can be downloaded using the IFU icon above
Real-Time PCR
Reagents in stock tubes
Ready-to-use PCR tubes
Research Use Only
CE marked as legacy IVD
Green FAM/SYBR Green I
Yellow HEX/JOE/VIC
Red Cy5
Orange ROX
Available
On request

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